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vildagliptin 100mg SR + sitagliptin 50 mg


Vildagliptin 100mg SR + Sitagliptin 50mg is a combination medication used in the management of type 2 diabetes. Both vildagliptin and sitagliptin belong to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors. They work by increasing the levels of incretin hormones, which stimulate insulin release and decrease the levels of glucagon, thereby helping to lower blood sugar levels. This combination is particularly useful when blood sugar is not adequately controlled with other medications or lifestyle changes alone.

Side Effects:-

  • Hypoglycemia: One of the potential side effects of vildagliptin and sitagliptin is hypoglycemia or low blood sugar levels. Symptoms may include sweating, shakiness, dizziness, confusion, and hunger. Patients taking this medication should be cautious, especially if they are also using insulin or other medications that can lower blood sugar.
  • Upper Respiratory Tract Infections: Some patients may experience upper respiratory tract infections, such as the common cold or sinusitis, while taking vildagliptin and sitagliptin. These infections are usually mild and resolve without specific treatment.
  • Headache and Dizziness: Headaches and dizziness are common side effects reported by some patients. These symptoms are usually mild and transient.
  • Gastrointestinal Issues: Digestive problems such as nausea, diarrhea, and abdominal discomfort may occur in some individuals. These side effects are usually temporary and improve over time.
  • Joint Pain: Joint pain or arthralgia may occur in some patients taking vildagliptin and sitagliptin. It is usually mild and temporary.
  • Skin Reactions: Rarely, some individuals may experience skin reactions such as rash or itching. If these occur, medical advice should be sought.


This medication is indicated for adults with type 2 diabetes mellitus who require additional treatment to improve glycemic control. It is usually prescribed when diet and exercise alone are not sufficient to control blood sugar levels. Vildagliptin 100mg SR + Sitagliptin 50mg can be used alone or in combination with other antidiabetic medications, such as metformin or sulfonylureas, depending on the patient’s needs.

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