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Polymyxin B Sulphate


Polymyxin B Sulphate is an antibiotic used to treat various bacterial infections, particularly those caused by Gram-negative bacteria. It is effective against a range of severe infections including those of the urinary tract, bloodstream, and meninges. Polymyxin B is particularly valuable in treating infections caused by multidrug-resistant organisms such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. It can be administered intravenously, intramuscularly, or topically, depending on the nature and location of the infection.

Side Effects:-

Like all medications, Polymyxin B Sulphate can cause side effects. Common side effects include pain at the injection site, dizziness, and upset stomach. More serious side effects may include nephrotoxicity, which affects the kidneys, and neurotoxicity, which can cause symptoms such as muscle weakness, numbness, and tingling. Allergic reactions, although rare, can occur and may present as rash, itching, swelling, severe dizziness, and difficulty breathing. It is crucial to monitor kidney function regularly during treatment, as Polymyxin B has a known risk of causing kidney damage.


Polymyxin B Sulphate is indicated for the treatment of infections caused by susceptible strains of Gram-negative bacteria. These include severe urinary tract infections, meningitis, septicemia, and infections of the respiratory system, eyes, and ears. It is also used in combination with other antibiotics to treat serious, life-threatening infections, particularly those caused by bacteria resistant to other treatments.

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