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Obeticholic acid (OCA) 10 mg is a medication prescribed for the treatment of primary biliary cholangitis (PBC), a chronic liver disease that affects the bile ducts. It works by activating the farnesoid X receptor (FXR), which regulates bile acid synthesis and transport in the liver and intestines. OCA helps to reduce the accumulation of toxic bile acids in the liver, slow disease progression, and improve liver function in patients with PBC. It is often used in combination with other medications or as monotherapy in individuals who do not respond adequately to other treatments. OCA can alleviate symptoms such as fatigue, itching, and jaundice, and may also delay the need for liver transplantation in some cases.

Side Effects:-

While OCA is effective in treating PBC, it may cause certain side effects in some individuals. Common side effects include pruritus (itching), fatigue, abdominal pain, constipation, and nausea. These side effects are usually mild to moderate in severity and often resolve with continued treatment. However, some patients may experience more serious adverse reactions such as liver toxicity, elevated cholesterol levels, or exacerbation of underlying liver disease. Close monitoring of liver function tests, lipid levels, and clinical symptoms is necessary to detect and manage any potential adverse effects. Patients should promptly report any unusual or persistent symptoms to their healthcare provider for proper evaluation and management.


OCA 10 mg tablets are indicated for the treatment of primary biliary cholangitis (PBC) in adults with an inadequate response to or intolerance of ursodeoxycholic acid (UDCA), the standard therapy for PBC. It is prescribed to slow the progression of liver damage, improve liver function, and alleviate symptoms associated with PBC, including fatigue, pruritus (itching), and elevated liver enzymes. OCA may be used alone or in combination with UDCA, depending on the individual patient’s response and treatment goals. Regular monitoring of liver function tests and clinical symptoms is essential to assess the effectiveness and safety of OCA therapy.

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