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Glimepiride 2mg + Metformin 500mg + voglibose 0.3mg


Glimepiride 2mg + Metformin 500mg + Voglibose 0.3mg is a combination medication used to manage type 2 diabetes mellitus. This medication helps to control blood sugar levels through three different mechanisms. Glimepiride increases insulin secretion from the pancreas, Metformin reduces glucose production in the liver and improves insulin sensitivity, and Voglibose delays the absorption of glucose in the intestines. Together, these actions help maintain better blood sugar control throughout the day.

Side Effects:-

  • Hypoglycemia: One of the main side effects of Glimepiride is hypoglycemia, which means low blood sugar levels. Symptoms of hypoglycemia include sweating, shakiness, dizziness, hunger, and confusion. Patients should be aware of these symptoms and know how to treat them quickly, often with a fast-acting source of glucose like candy or juice.
  • Gastrointestinal Issues: Metformin and Voglibose can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort. These symptoms are generally temporary and usually decrease as the body adjusts to the medication. Voglibose, in particular, can cause flatulence due to its action in the intestines.
  • Weight Gain: Glimepiride may cause weight gain in some patients. Monitoring weight regularly and maintaining a balanced diet and exercise regimen can help manage this side effect.
  • Lactic Acidosis: Metformin, though rare, can lead to a serious condition called lactic acidosis. Symptoms include muscle pain, difficulty breathing, stomach pain, dizziness, and irregular heartbeat. The risk is higher in patients with kidney or liver problems.
  • Allergic Reactions: Some patients may experience allergic reactions to this medication, which can include rash, itching, swelling, and difficulty breathing. If these symptoms occur, immediate medical attention is necessary


This combination medication is indicated for patients with type 2 diabetes who require more than one medication to achieve adequate blood sugar control. It is especially useful for patients whose blood sugar levels are not well managed with diet, exercise, and monotherapy. This medication provides a comprehensive approach by targeting different aspects of glucose regulation, making it effective in reducing blood sugar levels.

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