Sunwin Healthcare PVT LTD



Esomeprazole 40 mg + Levosulpiride 75mg


Esomeprazole 40 mg + Levosulpiride 75 mg:

  • This combination medication is used primarily for the treatment and management of gastrointestinal conditions, especially those involving excessive stomach acid production and poor gastric motility. Key uses include:
  • Gastroesophageal Reflux Disease (GERD): Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, providing relief from GERD symptoms such as heartburn and acid reflux. Levosulpiride enhances gastric motility, helping to prevent reflux.
  • Functional Dyspepsia: The combination helps treat functional dyspepsia, which includes symptoms like bloating, nausea, early satiety, and upper abdominal discomfort. Esomeprazole reduces stomach acid, while Levosulpiride improves stomach emptying and gastrointestinal motility.
  • Peptic Ulcers: Esomeprazole aids in healing peptic ulcers by decreasing stomach acid, allowing ulcers to heal more effectively. Levosulpiride’s prokinetic effects can help reduce associated symptoms.
  • Gastroparesis: Levosulpiride is effective in managing gastroparesis by enhancing gastric emptying, which reduces symptoms like nausea, vomiting, and abdominal pain.

Side Effects:-

Common side effects of Esomeprazole 40 mg + Levosulpiride 75 mg include:

  • Headache: Both Esomeprazole and Levosulpiride can cause headaches in some individuals.
  • Gastrointestinal Issues: Side effects such as nausea, vomiting, diarrhea, constipation, and abdominal pain may occur. Taking the medication with food might help mitigate these effects.
  • Drowsiness and Dizziness: Levosulpiride may cause drowsiness or dizziness. It is advisable to avoid driving or operating heavy machinery if these symptoms occur.
  • Dry Mouth: Some users might experience dry mouth as a side effect of Levosulpiride.
  • Fatigue: Feeling tired or fatigued can occur with the use of these medications.


General Use:

  • The combination of Esomeprazole 40 mg and Levosulpiride 75 mg is indicated for the treatment and management of various gastrointestinal conditions. It is particularly useful for:
  • Management of GERD: This combination effectively manages GERD symptoms by reducing stomach acid production and improving gastric motility, providing relief from heartburn and acid reflux.
  • Treatment of Functional Dyspepsia: It helps alleviate symptoms of functional dyspepsia, such as bloating, nausea, and upper abdominal discomfort, by reducing acid production and enhancing stomach emptying.
  • Healing Peptic Ulcers: Esomeprazole promotes the healing of peptic ulcers by decreasing stomach acid, while Levosulpiride reduces symptoms through its prokinetic effects.
  • Gastroparesis Relief: Levosulpiride helps manage gastroparesis by promoting faster gastric emptying, reducing symptoms like nausea, vomiting, and abdominal pain.
  • In summary, Esomeprazole 40 mg + Levosulpiride 75 mg is an effective combination medication used to treat and manage various gastrointestinal conditions, including GERD, functional dyspepsia, peptic ulcers, and gastroparesis. It is generally safe and effective when used as directed, but users should be mindful of potential side effects and consult with a healthcare professional to ensure the medication is appropriate for their specific health needs.

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