Composition:-
Imipenem 1gm+Cilastatin 1gm
Uses:-
Imipenem 1gm and Cilastatin 1gm combination is a powerful antibiotic used to treat a variety of severe bacterial infections. Imipenem is a beta-lactam antibiotic that works by inhibiting bacterial cell wall synthesis, leading to bacterial death. Cilastatin is included to inhibit the renal enzyme dehydropeptidase I, which prevents the breakdown of imipenem in the kidneys, thereby increasing its effectiveness. This combination is used to treat infections such as complicated urinary tract infections, respiratory tract infections, intra-abdominal infections, skin and soft tissue infections, and septicemia.
Side Effects:-
Common side effects of this medication include nausea, vomiting, diarrhea, and pain or redness at the injection site. Some patients may experience headache, dizziness, or rash. Serious side effects, though less common, can include severe allergic reactions (anaphylaxis), seizures, severe diarrhea (Clostridium difficile-associated diarrhea), and liver dysfunction. If you experience any severe side effects or signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek medical attention immediately.
Indication:-
The combination of Imipenem and Cilastatin is indicated for the treatment of serious bacterial infections caused by susceptible strains of bacteria. It is particularly effective against infections that are resistant to other antibiotics. The combination is used for infections in various parts of the body, including the lower respiratory tract, urinary tract, abdomen, skin and soft tissues, and in cases of bacterial septicemia. It is also used to treat infections caused by multi-resistant bacteria in hospitalized patients.
