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Colistin sulphate 12.5 mg is a medication primarily used to treat bacterial infections, particularly those caused by multidrug-resistant strains. It belongs to a class of antibiotics known as polymyxins, which work by disrupting the outer membrane of bacteria, leading to their destruction. Colistin is commonly used to treat infections such as pneumonia, urinary tract infections, and bloodstream infections caused by bacteria such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. It is often considered a last-resort antibiotic due to its potential for side effects and the risk of antibiotic resistance.

Side Effects:-

While colistin sulphate 12.5 mg can effectively treat bacterial infections, it may cause some side effects in certain individuals. Common side effects may include nausea, vomiting, diarrhea, and stomach upset. These side effects are usually mild and temporary. However, in rare cases, colistin sulphate may cause more serious side effects such as kidney damage, neurotoxicity (e.g., tingling or numbness in the limbs), and respiratory problems. It is important to monitor for any unusual symptoms and report them to a healthcare professional promptly.


Colistin sulphate 12.5 mg is indicated for the treatment of bacterial infections caused by multidrug-resistant strains, particularly those resistant to other antibiotics. It is often used when other antibiotics have failed to effectively treat the infection or when the bacteria causing the infection are known to be resistant to other antibiotics. Colistin works by targeting the bacterial cell membrane, leading to the disruption of the bacterial cell and eventual cell death. It is important to use colistin sulphate under the guidance of a healthcare professional and to follow the recommended dosage and treatment duration to ensure optimal effectiveness and minimize the risk of side effects.

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