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Ampicillin 1g Sulbactam 500mg


Ampicillin and Sulbactam combination is an antibiotic medication used to treat various bacterial infections. Here are its main uses:

  • Bacterial Infections: This combination is effective against a wide range of bacterial infections caused by susceptible bacteria, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, and gynecological infections.
  • Respiratory Infections: It is used to treat respiratory infections such as pneumonia, bronchitis, and sinusitis caused by susceptible bacteria.
  • Urinary Tract Infections (UTIs): Ampicillin-Sulbactam is effective against UTIs, including cystitis and pyelonephritis, which are caused by bacteria.
  • Skin and Soft Tissue Infections: It can treat skin infections like cellulitis, wound infections, and abscesses caused by susceptible bacteria.
  • Intra-abdominal Infections: This combination is used to treat intra-abdominal infections such as peritonitis and appendicitis.

Side Effects:-

While ampicillin-sulbactam is generally safe for most people, it may cause some side effects. Here are potential side effects:

  • Diarrhea: One of the common side effects is diarrhea, which may range from mild to severe. It can sometimes be a sign of a serious intestinal infection.
  • Allergic Reactions: Some individuals may experience allergic reactions such as rash, itching, swelling, or difficulty breathing. Severe allergic reactions are rare but require immediate medical attention.
  • Nausea and Vomiting: Ampicillin-sulbactam may cause nausea, vomiting, or stomach upset in some people.
  • Skin Reactions: It may lead to skin reactions such as itching, hives, or skin rash.
  • Injection Site Reactions: When administered intravenously or intramuscularly, it may cause pain, redness, or swelling at the injection site.
  • Rare Side Effects: Rarely, it may cause more serious side effects such as liver problems, blood disorders, or severe skin reactions.


Ampicillin 1g + Sulbactam 500mg is indicated for:

  • Bacterial Infections: Used to treat various bacterial infections caused by susceptible organisms, including respiratory, urinary tract, skin, soft tissue, and intra-abdominal infections.
  • Mixed Infections: Effective against polymicrobial infections where multiple types of bacteria are involved.
  • Hospital-acquired Infections: It may be used for treating infections acquired in the hospital setting.
  • Empirical Therapy: Sometimes prescribed as empirical therapy before the specific causative bacteria are identified through culture and sensitivity testing.
  • Combination Therapy: Often used in combination with other antibiotics for synergistic effects in severe infections.

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