Droterin-M is a combination medication for the treatment of abdominal pain and spasm resulting from smooth muscle contraction. Drotaverine is an antispasmodic which works by relaxing the muscles in the stomach and gut (intestine).Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID). This combination is particularly useful in the therapy of menstrual pain, abdominal colic and spasmodic pain involving the GI and urinary tract.